Monday, November 12, 2007

Public Question: Glucosamine

By SL,
1) I have doubt abt the efficacy of them and also, isn't glucosamine will be better if it is combined with chondriotin? what is the main difference of taking powder over capsule aside more convenient?
2) You mentioned that glucosamine is not working well in topical form, but some studies actually showed that topical form works better as it is avoided from first pass metabolism, so more will be deposited into the join.
hope that you can help me to clear my doubts out of my mind!
good day!

Ask the pharmacist
1) U may try adding on chondroitin sulphate if glucosamine alone is not effective at full dose. No research shows chondroitin combination will have more benefits compare with glucosamine alone.
2) I never come across topical glucosamine before.
There is also no research showing that glucosamine can be absorbed topically. If u have topical glucosamine cream, mind to share with me the ingredients? Those cream may have menthol, methysalicylate, or camphor which can give symptomatic relief becoz of its counterirritant effect.

SL, u r correct in saying studies actually showed that topical form works better as it is avoided from first pass metabolism, just that it does not apply to glucosamine.

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